![]() ![]() In order to estimate the pooled mean platelet volume and mean difference, random effect model was done. The analysis was done by Stata version 11. For studies meeting the eligibility criteria, the first author’s name, publication year, population, study design, study area, sample size, mean platelet volume and standard deviation were extracted and entered in to Microsoft-excel. Observational (cohort, cross-sectional and case-control) studies, published in English language and conducted on IBD were included. In addition, articles were directly searched in Google Scholar to account for the studies omission in searching bibliographic databases. Therefore, the aim of this review was determining the estimated pooled mean platelet volume and mean difference in inflammatory bowel disease to elucidate its potential diagnostic value.Īrticles were extensively searched in bibliographic databases using Medical Subject Heading and entry phrases or terms. ![]() In IBD, platelet parameters underwent several changes. It can affect alimentary canals such as colon, rectum, ileum and other parts. Inflammatory bowel disease (IBD) is a chronic gastrointestinal tract inflammatory state, which is affecting millions of individuals in the world. The indication of VTE prophylaxis should be determined individually, considering other risks. D-dimer levels were often elevated in patients with WAIHA, indicating that the coagulation was activated in a considerable number of patients, but not to such a level as to be associated with clinically overt thrombosis.Ĭonclusion Thrombotic complications occur infrequently in Japanese WAIHA patients, and these individuals do not appear to be at a particularly increased risk of thrombosis because of WAIHA. There was no mortality associated with thrombosis. No venous thrombosis occurred in any patients during the follow-up period. However, all three of those patients had other known risks for thrombosis, with only one taking thrombotic prophylaxis. ![]() Results No patient presented with thrombosis, and over a median observation period of 15 months, 3 patients had ischemic cerebral vascular accidents. Twenty-nine patients were diagnosed as primary cases and 18 as secondary cases, and 10 patients were diagnosed with Evans syndrome. Patients and Methods Forty-seven consecutive patients with warm WAIHA were retrospectively studied. Thrombotic complications and features of Japanese warm AIHA (WAIHA) patients were studied to see if Japanese patients were at an increased risk of thrombosis and should receive prophylaxis for VTE. However, the occurrence of thrombosis in Asian patients has not been specifically studied. Objective Patients with autoimmune hemolytic anemia (AIHA) are considered to be at an increased risk of thrombosis, and prophylaxis for venous thromboembolism (VTE) is often recommended. ![]()
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